Recombinant protein of human l

gene_symbol：LILRB2
Description：Recombinant protein of human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 (LILRB2), transcript variant 2
Accn：NM_001080978
Unipro ID
Synonyms：CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10
Species：Human
Amount：10 ug
Delivery time：2周
Expression sequence：Gln22-His458
Tags：C-His
PredictedMW：48.6 kDa
Buffer：Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Stability：Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Bioactivity
Purity：>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration：lot specific
Preparation
Endotoxin：< 0.1 EU per µg protein as determined by LAL test
Shipping
Background：This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]