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Description:Recombinant protein of human advanced glycosylation end product-specific receptor (AGER), transcript variant 1
Accn:NM_001136
Unipro ID:Q15109
Synonyms:RAGE; SCARJ1; sRAGE
Species:Human
Amount:10 ug
Delivery time:2周
Expression sequence:Ala23-Ala344
Tags:C-His
PredictedMW:35.2 kDa
Buffer:Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Stability:Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Bioactivity:Binding assay (PMID: 29420566)
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:lot specific
Preparation
Endotoxin:< 0.1 EU per µg protein as determined by LAL test
Shipping
Background:The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
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文献和实验Recombinant Protein Production in Yeasts
Recombinant protein production is a multibillion-dollar market. The development of a new product begins with the choice of a production host. While one single perfect host for every protein does not exist, several expression systems ranging
Site‐Specific Protein Labeling with SNAP‐Tags
. Griffin, B.A., Adams, S.R., and Tsien, R.Y. 1998. Specific covalent labeling of recombinant protein molecules inside live cells. Science 281:269–272.
). After superinfection with helper phage and induction of P lac , Fd (composed of V H and C H 1 domains) and κ-or α-L chains assemble into Fab fragments in the periplasm of the Escherichia coli host strain, and the Fab-ΔpIII protein complex is displayed at one end
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