Recombinant protein of human s

gene_symbol：SARM
Description：Recombinant protein of human sterile alpha and TIR motif containing 1 (SARM1), 20 µg
Accn：NM_015077
Unipro ID：Q6SZW1
Synonyms：hSARM1; HsTIR; MyD88-5; SAMD2; SARM
Species：Human
Amount：20 ug
Delivery time：现货
Expression sequence：Recombinant protein was produced with TrueORF clone, [RC215903]. Click on the TrueORF clone link to view cDNA and protein sequences.
Tags：C-Myc/DDK
PredictedMW：79.2 kDa
Buffer：25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.1 µg/µL as determined by microplate BCA method
Preparation：Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Endotoxin
Shipping
Background：Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.[UniProtKB/Swiss-Prot Function]