Recombinant protein of human troponin I type 2 (skeletal, fast) (TNNI2), transcript variant 1, 20 µg

Recombinant protein of human t

roponin I type 2 (skeletal, fast) (TNNI2), transcript variant 1, 20 µg
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  • ¥2900
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  • TP305676
  • 2025年09月05日
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    gene_symbol:Troponin I fast skeletal muscle
    Description:Recombinant protein of human troponin I type 2 (skeletal, fast) (TNNI2), transcript variant 1, 20 µg
    Accn:NM_003282
    Unipro ID:P48788
    Synonyms:AMCD2B; DA2B; DA2B1; FSSV; fsTnI
    Species:Human
    Amount:20 ug
    Delivery time:现货
    Expression sequence:>RC205676 protein sequence Red=Cloning site Green=Tags(s) MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHA KIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRAN LKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES TRTRPLEQKLISEEDLAANDILDYKDDDDKV
    Tags:C-Myc/DDK
    PredictedMW:21.2 kDa
    Buffer:25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
    Stability:Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
    Bioactivity
    Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
    Concentration:>0.05 µg/µL as determined by microplate BCA method
    Preparation:Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
    Endotoxin
    Shipping
    Background:This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]

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