BRAF V600E Rabbit monoclonal a

gene_symbol：BRAF
predicted_size：null
Uniprot ID：P1556
description：BRAF V600E Rabbit monoclonal antibody,clone OTIR1F3
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
immunogen：Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human BRAF V600E (NP_004324). The exact sequence is proprietary.
recommended_dilution：WB 1:500
predicted_size：null
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Rabbit
applications：WB
reactivities：Human