ASC / TMS1 Rabbit polyclonal A

gene_symbol：PYCARD
predicted_size：15kDa/19kDa/21kDa
Uniprot ID：Q9ULZ3
description：ASC / TMS1 Rabbit polyclonal Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
immunogen：Recombinant protein of human ASC / TMS1
recommended_dilution：WB,1:500 - 1:2000 IHC,1:50 - 1:200 IF,1:50 - 1:200 IP,1:50 - 1:200
predicted_size：15kDa/19kDa/21kDa
buffer：Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
host_species：Rabbit
applications：IF, IHC, IP, WB
reactivities：Human, Mouse, Rat