CARD16 rabbit polyclonal antib

gene_symbol：CARD16
predicted_size：23 kDa
Uniprot ID：Q5EG5
description：CARD16 rabbit polyclonal antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
immunogen：Synthetic peptide of human CARD16
recommended_dilution：WB: 200-1000 WB positive control: HEPG2 cell lysate IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
predicted_size：23 kDa
buffer：pH7.4 PBS, 0.05% NaN3, 40% Glycerol
host_species：Rabbit
applications：IHC, WB
reactivities：Human