Rabbit Polyclonal Anti-SLC7A11

gene_symbol：SLC7A11
predicted_size：55 kDa
Uniprot ID：Q9UPY5
description：Rabbit Polyclonal Anti-SLC7A11 Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
immunogen：Synthetic peptide of human SLC7A11
recommended_dilution：WB: 1000-5000 WB positive control: HepG2 and 293T cell lysates IHC: 50-100 Positive control: Human cervical cancer Predicted cell location: Cytoplasm and Cell membrane
predicted_size：55 kDa
buffer：pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
host_species：Rabbit
applications：IHC, WB
reactivities：Human, Mouse