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- 详细信息
- 技术资料
- 免疫原:
Spleen cells or thymocyte membranes
- 亚型:
Cell membrane Single-pass type I membrane protein
- 形态:
粉末
- 保存条件:
Store at 2-8℃ in dark.Do not freeze.
- 克隆性:
Monoclonal Antibody
- 适应物种:
Mouse
- 保质期:
咨询
- 抗原来源:
Spleen cells or thymocyte membranes
- 级别:
实验级别
- 库存:
咨询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rat
- 应用范围:
IF
- 浓度:
IF 1:250-1000.
- 靶点:
CD8a(AF647)
- 抗体英文名:
Anti-CD8a(AF647) Monoclonal Antibody
- 抗体名:
Anti-CD8a(AF647) Monoclonal Antibody
- 规格:
25ug/100ug
| 规格: | 25ug | 产品价格: | ¥550.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥1400.0 |
CD8a;CD8a antigen;CD8a molecule;CD8A_MOUSE;CD8A_HUMAN;Leu2;MAL;p32;PE标记的大鼠CD8a单克隆抗体;CD8a(AF647);12525;P01731
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains.It can be present as a homodimer of CD8 or as a heterodimer of CD8 and CD8 (PMID: 3264320;8253791).CD8 is found on most thymocytes.The majority of class I-restricted T cells express mostly the CD8 heterodimer while CD8 homodimers alone have been found on some gut intraepithelial T cells on some T cell receptor (TCR) T cells and on NK cells (PMID: 2111591;1831127;8420975).CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079).During T cell development CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084).

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