STAT6 Rabbit Monoclonal Antibo

ProductName：STAT6 Rabbit Monoclonal Antibody [Clone ID: UMAB300]
description：STAT6 Rabbit monoclonal antibody,clone UMAB300
symbol：STAT6
synonyms：D12S1644; IL-4-STAT; STAT6B; STAT6C
locusid：6778
Concentration：1.00mg/ml
sub_category：Primary Antibodies
uniprot_id：P42226
Applications：IHC
CNdelivery：2周
RecommendDilution：IHC 1:1000,WB 1:5000
Reactivity：Human
Immunogen：Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human STAT6 (NP_003144). The exact sequence is proprietary.
Purification：Purified from cell culture supernatant by affinity chromatography(protein A/G)
Conjugation：Unconjugated
ProteinFamilies：Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
ProteinPathways：Jak-STAT signaling pathway
GeneName：signal transducer and activator of transcription 6
Background：The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter：IgG
predicted_size：94.2 kDa