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- 详细信息
- 技术资料
- 保存条件:
Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
- 克隆性:
Monoclonal
- 适应物种:
null
- 宿主:
Rabbit
- 规格:
30 ul
ProductName:KIR3DL1 Rabbit Monoclonal Antibody [Clone ID: OTIR1A9]
description:KIR3DL1 Rabbit monoclonal antibody, clone OTIR1A9
symbol:KIR3DL1
synonyms:null
locusid:3811
Concentration:1 mg/ml
sub_category:Primary Antibodies
uniprot_id:P43629
Applications:WB
CNdelivery:2周
RecommendDilution:WB 1:5000
Reactivity:Human
Immunogen:Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human KIR3DL1 (NP_037421). The exact sequence is proprietary.
Purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation:Unconjugated
ProteinFamilies:null
ProteinPathways:null
GeneName:killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
Background:Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
Buffer:PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter:IgG
predicted_size:49.1kDa
description:KIR3DL1 Rabbit monoclonal antibody, clone OTIR1A9
symbol:KIR3DL1
synonyms:null
locusid:3811
Concentration:1 mg/ml
sub_category:Primary Antibodies
uniprot_id:P43629
Applications:WB
CNdelivery:2周
RecommendDilution:WB 1:5000
Reactivity:Human
Immunogen:Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human KIR3DL1 (NP_037421). The exact sequence is proprietary.
Purification:Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation:Unconjugated
ProteinFamilies:null
ProteinPathways:null
GeneName:killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
Background:Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
Buffer:PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter:IgG
predicted_size:49.1kDa
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KIR3DL1 Rabbit Monoclonal Antibody [Clone ID: OTIR1A9]
¥1900


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