BubR1 (BUB1B) Rabbit Monoclona

ProductName：BubR1 (BUB1B) Rabbit Monoclonal Antibody
description：BubR1 Antibody
symbol：BUB1B
synonyms：BUB1B; BUBR1; hBUBR1; MAD3L; Mitotic checkpoint kinase MAD3L Protein SSK1; SSK1
locusid：701
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：O60566
Applications：FC, IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB 1:1000~1:5000 IHC 1:50~1:200 IP 1:30 FC 1:50
Reactivity：Human, Mouse, Rat
Immunogen：A synthesized peptide derived from human BubR1
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：BUB1 mitotic checkpoint serine/threonine kinase B
Background：Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：120kDa