Tryptophan Hydroxylase (TPH1)

ProductName：Tryptophan Hydroxylase (TPH1) Rabbit Monoclonal Antibody
description：TPH1 Antibody
symbol：TPH1
synonyms：MGC119994; TPH1; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan Hydroxylase
locusid：7166
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P17752
Applications：IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Reactivity：Human, Mouse, Rat
Immunogen：A synthesized peptide derived from human TPH1
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：tryptophan hydroxylase 1
Background：Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin by converting tryptophan to 5-hydroxy-L-tryptophan. Two isoforms of TPH exist: TPH-1 is mainly expressed in the periphery, whereas the expression of TPH-2 is restricted to neuronal cells and the central nervous system. Most of the serotonin found throughout the body is synthesized by TPH-1 in enterochromaffin cells of the gastrointestinal tract. Targeted disruption of the tph1 gene results in low levels of circulating and tissue serotonin.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：51kDa