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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at +4°C short term. Store at -23°C long term. Avoid freeze / thaw cycle.
- 克隆性:
Monoclonal
- 适应物种:
null
- 宿主:
Rabbit
- 规格:
100 ul
description:Lamin B Receptor Antibody
symbol:LBR
synonyms:DHCR14B; LBR; LMN2R; PHA; TDRD18
locusid:3930
Concentration:lot specific
sub_category:Primary Antibodies
uniprot_id:Q14739
Applications:ICC/IF, IHC, IP, WB
CNdelivery:2周
RecommendDilution:WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:30
Reactivity:Human, Rat
Immunogen:A synthesized peptide derived from human Lamin B Receptor
Purification:Affinity-chromatography
Conjugation:Unconjugated
ProteinFamilies:null
ProteinPathways:null
GeneName:lamin B receptor
Background:The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter:IgG
predicted_size:70kDa
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文献和实验Chimerization of a Monoclonal Antibody for Treating Hodgkin's Lymphoma
Conventionally, monoclonal antibodies (MAbs) are generated by fusing B cells from an immunized animal with myeloma cells from the same species (1 ). Several murine MAb have already been employed for in vivo diagnosis and therapy, including
One of the major challenges in human B cell immunology field has been the objective to establish stable monoclonal cells lines that express the B cell receptor (BCR) on their cell surface and secrete antibodies. Such a system is extremely
A method is described for affinity isolation of antigen-specific circulating B cells of interest for subsequent generation of immune antibody phage display libraries. This approach should overcome the problem of low yields of monoclonal
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