- ￥1999
- null
- TA422546
- 2025年07月12日
- Rabbit
- null
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- 详细信息
- 技术资料
- 保存条件：
Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle.
- 克隆性：
Monoclonal
- 适应物种：
null
- 宿主：
Rabbit
- 规格：
100 ul
ProductName：EEA1 Rabbit Monoclonal Antibody
description：EEA1 Antibody
symbol：EEA1
synonyms：Early endosome antigen 1; EEA1; MST105; ZFYVE2
locusid：8411
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q15075
Applications：ICC/IF, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 ICC/IF 1:50~1:200
Reactivity：Human, Mouse, Rat
Immunogen：A synthesized peptide derived from human EEA1
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：early endosome antigen 1
Background：EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1-2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4-6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7).
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：170kDa
description：EEA1 Antibody
symbol：EEA1
synonyms：Early endosome antigen 1; EEA1; MST105; ZFYVE2
locusid：8411
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q15075
Applications：ICC/IF, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 ICC/IF 1:50~1:200
Reactivity：Human, Mouse, Rat
Immunogen：A synthesized peptide derived from human EEA1
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：early endosome antigen 1
Background：EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1-2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4-6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7).
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：170kDa
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技术资料暂无技术资料 索取技术资料
EEA1 Rabbit Monoclonal Antibody
￥1999
