HSF1 Rabbit Monoclonal Antibod

ProductName：HSF1 Rabbit Monoclonal Antibody
description：Phospho-HSF1 (S326) Antibody
symbol：HSF1
synonyms：Heat shock factor protein 1; Heat shock transcription factor 1; HSF1; HSTF 1; HSTF1
locusid：3297
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q00613
Applications：FC, ICC/IF, IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:50
Reactivity：Human
Immunogen：A synthesized peptide derived from human Phospho-HSF1 (S326)
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：heat shock transcription factor 1
Background：Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：82kDa