- ￥1999
- null
- TA422258
- 2025年07月14日
- Rabbit
- null
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- 详细信息
- 技术资料
- 保存条件：
Store at +4°C short term. Store at -23°C long term. Avoid freeze / thaw cycle.
- 克隆性：
Monoclonal
- 适应物种：
null
- 宿主：
Rabbit
- 规格：
100 ul
ProductName：PMS2 Rabbit Monoclonal Antibody
description：PMS2 Antibody
symbol：PMS2
synonyms：DNA mismatch repair gene; DNA mismatch repair protein PMS2; HNPCC4; PMS1 protein homolog 2
locusid：5395
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P54278
Applications：FC, ICC/IF, IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Reactivity：Human
Immunogen：A synthesized peptide derived from human PMS2
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：PMS1 homolog 2, mismatch repair system component
Background：Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：110kDa
description：PMS2 Antibody
symbol：PMS2
synonyms：DNA mismatch repair gene; DNA mismatch repair protein PMS2; HNPCC4; PMS1 protein homolog 2
locusid：5395
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P54278
Applications：FC, ICC/IF, IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Reactivity：Human
Immunogen：A synthesized peptide derived from human PMS2
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：PMS1 homolog 2, mismatch repair system component
Background：Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：110kDa
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技术资料暂无技术资料 索取技术资料
PMS2 Rabbit Monoclonal Antibody
￥1999
