Pleiotrophin (PTN) Rabbit Mono

ProductName：Pleiotrophin (PTN) Rabbit Monoclonal Antibody [Clone ID: R01-2J3]
description：PTN Rabbit monoclonal Antibody
symbol：PTN
synonyms：HARP; HB-GAM; HBBM; HBGF-8; HBGF8; HBNF; HBNF-1; HBNF1; NEGF1; OSF-1; pleiotrophin
locusid：5764
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P21246
Applications：IP, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000-1/5000
IP: 1/20
Reactivity：Human, Rat
Immunogen：A synthetic peptide of human PTN
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：pleiotrophin
Background：Swiss-Prot Acc.P21246.Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 19 kDa; Observed MW: 19 kDa