Prostaglandin D Synthase (PTGD

ProductName：Prostaglandin D Synthase (PTGDS) Rabbit Monoclonal Antibody [Clone ID: R06-1C5]
description：Prostaglandin D Synthase Rabbit monoclonal Antibody
symbol：PTGDS
synonyms：Cerebrin-28; L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
locusid：5730
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P41222
Applications：IF, IHC, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
IHC: 1/20
ICC/IF: 1/20
Reactivity：Human, Mouse, Rat
Immunogen：A synthetic peptide of human Prostaglandin D Synthase
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：prostaglandin D2 synthase
Background：Swiss-Prot Acc.P41222.Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-Tis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 21 kDa; Observed MW: 26 kDa