Proteasome subunit alpha type

ProductName：Proteasome subunit alpha type 6 (PSMA6) Rabbit Monoclonal Antibody [Clone ID: R01-4I2]
description：Proteasome alpha 6 Rabbit monoclonal Antibody
symbol：PSMA6
synonyms：IOTA; MGC2333; MGC22756; MGC23846; p27K; PROS-27; PROS27
locusid：5687
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P60900
Applications：IF, WB
CNdelivery：2周
RecommendDilution：WB: 1/2000-1/10000
ICC/IF: 1/50-1/100
Reactivity：Human, Mouse, Rat
Immunogen：A synthetic peptide of human Proteasome subunit alpha type 6
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：proteasome subunit alpha 6
Background：Swiss-Prot Acc.P60900.Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 27 kDa; Observed MW: 27 kDa