- ￥1999
- null
- TA385060
- 2025年07月10日
- Rabbit
- null
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 克隆性：
Monoclonal
- 适应物种：
null
- 宿主：
Rabbit
- 规格：
100 ul
description：Prion Protein Rabbit monoclonal Antibody
symbol：PRNP
synonyms：AA960666; AI325101; CD230; Prn; Prn-i; Prn-p; PrP; prP27-30; prP33-35C; PrP; PrPC; PrPSc; Sinc
locusid：5621
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P04156
Applications：IHC, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000-1/5000
IHC: 1/20
Reactivity：Human, Mouse, Rat
Immunogen：A synthetic peptide of human Prion protein PrP
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：prion protein
Background：Swiss-Prot Acc.P04156.Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) . Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains .
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 28 kDa; Observed MW: 28 kDa
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文献和实验Studies of the Ubiquitin Proteasome System
polyclonal rabbit anti‐ubiquitin (commercially available or prepared as in protocol 31 ) or monoclonal anti‐ubiquitin in TBST/BSA TBST buffer (see recipe ) [125 I]protein A (MP
population is termed monoclonal . It recognizes a single epitope on the antigenic protein. Antibody producing B lymphocytes can be isolated from the spleen or from lymph nodes. However, they have a finite life span in culture, i.e
Chromatin Immunoprecipitation (ChIPs) Cloning Protocol (Farnham Lab)
). Day 2 14. If you are not using rabbit polyclonal antibodies (ie. monoclonal antibodies, ect), add 1 ug of an appropriate secondary antibody (rabbit) and incubate for an additional 1 hour. 15. Add
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