![MIB1 Rabbit Monoclonal Antibody [Clone ID: R06-3D9]](https://img1.dxycdn.com/p/s14/2025/0217/601/8427578297774731981.png)
- ￥1999
- null
- TA384779
- 2025年07月08日
- Rabbit
- null
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- 详细信息
- 技术资料
- 保存条件：
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 克隆性：
Monoclonal
- 适应物种：
null
- 宿主：
Rabbit
- 规格：
100 ul
ProductName：MIB1 Rabbit Monoclonal Antibody [Clone ID: R06-3D9]
description：MIB1 Rabbit monoclonal Antibody
symbol：MIB1
synonyms：DIP-1; DIP1; DKFZp686I0769; DKFZp761M1710; FLJ90676; KIAA1323; MGC129659; MGC129660; MIB; ZZANK2; ZZZ6
locusid：57534
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q86YT6
Applications：WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
Reactivity：Human, Mouse
Immunogen：A synthetic peptide of human Mib1
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：mindbomb E3 ubiquitin protein ligase 1
Background：Swiss-Prot Acc.Q86YT6.E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis . Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 110 kDa; Observed MW: 110 kDa
description：MIB1 Rabbit monoclonal Antibody
symbol：MIB1
synonyms：DIP-1; DIP1; DKFZp686I0769; DKFZp761M1710; FLJ90676; KIAA1323; MGC129659; MGC129660; MIB; ZZANK2; ZZZ6
locusid：57534
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q86YT6
Applications：WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
Reactivity：Human, Mouse
Immunogen：A synthetic peptide of human Mib1
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：mindbomb E3 ubiquitin protein ligase 1
Background：Swiss-Prot Acc.Q86YT6.E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis . Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 110 kDa; Observed MW: 110 kDa
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MIB1 Rabbit Monoclonal Antibody [Clone ID: R06-3D9]
￥1999
