Myelin Basic Protein (MBP) Rab

ProductName：Myelin Basic Protein (MBP) Rabbit Monoclonal Antibody [Clone ID: R07-4I6]
description：Myelin Basic Protein Rabbit monoclonal Antibody
symbol：MBP
synonyms：Golli-mbp; MGC99675; OTTHUMP00000174383
locusid：4155
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P02686
Applications：WB
CNdelivery：2周
RecommendDilution：WB: 1/2000-1/10000
Reactivity：Human, Rat
Immunogen：Recombinant protein of human Myelin Basic Protein
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：myelin basic protein
Background：Swiss-Prot Acc.P02686.The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 33 kDa; Observed MW: 18 kDa