Aspartate Aminotransferase (GO

ProductName：Aspartate Aminotransferase (GOT1) Rabbit Monoclonal Antibody [Clone ID: R05-6C1]
description：Aspartate Aminotransferase Rabbit monoclonal Antibody
symbol：GOT1
synonyms：GIG18
locusid：2805
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P17174
Applications：IF, IHC, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
IHC: 1/20-1/100
ICC/IF: 1/100-1/100
Reactivity：Human, Mouse, Rat
Immunogen：A synthetic peptide of human Aspartate Aminotransferase
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：glutamic-oxaloacetic transaminase 1
Background：Swiss-Prot Acc.P17174.Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 46 kDa; Observed MW: 46 kDa