FKBP52 (FKBP4) Rabbit Monoclon

ProductName：FKBP52 (FKBP4) Rabbit Monoclonal Antibody [Clone ID: R03-4A3]
description：FKBP52 Rabbit monoclonal Antibody
symbol：FKBP4
synonyms：FKBP52; FKBP59; HBI; Hsp56; p52; PPIase; rotamase
locusid：2288
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q02790
Applications：IF, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000-1/5000
ICC/IF: 1/20-1/50
Reactivity：Human, Mouse, Rat, Hamster
Immunogen：A synthetic peptide of human FKBP52
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：FK506 binding protein 4
Background：Swiss-Prot Acc.Q02790.Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 52 kDa; Observed MW: 52 kDa