Non Neuronal Enolase (ENO1) Ra

ProductName：Non Neuronal Enolase (ENO1) Rabbit Monoclonal Antibody [Clone ID: R01-4C8]
description：ENO1 Rabbit monoclonal Antibody
symbol：ENO1
synonyms：ENO1L1; MBP-1; MBPB1; MPB-1; MPB1; NNE; PPH; tau-crystallin
locusid：2023
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P06733
Applications：IF, IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
IHC: 1/500
ICC/IF: 1/100
IP: 1/20
Reactivity：Human, Mouse, Rat
Immunogen：A synthetic peptide of human ENO1
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：enolase 1
Background：Swiss-Prot Acc.P06733.Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.MiscellaneousUsed as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. Also marker for endometriosis. Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies. Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 47 kDa; Observed MW: 47 kDa