Caldesmon (CALD1) Rabbit Monoc

ProductName：Caldesmon (CALD1) Rabbit Monoclonal Antibody [Clone ID: R05-3D2]
description：Caldesmon Rabbit monoclonal Antibody
symbol：CALD1
synonyms：CAD; CDM; H-CAD; HCAD; L-CAD; LCAD; MGC21352; NAG22; OTTHUMP00000207949; OTTHUMP00000207954
locusid：800
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q05682
Applications：IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB: 1/2000-1/10000
IHC: 1/20
IP: 1/20
Reactivity：Human, Mouse, Rat
Immunogen：A synthetic peptide of human Caldesmon
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：caldesmon 1
Background：Swiss-Prot Acc.Q05682.Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration .
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 93 kDa; Observed MW: 70-80 kDa