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- 详细信息
- 技术资料
- 保存条件:
充氩
- 英文名:
6-Nitroveratraldehyde
- 库存:
现货
- 供应商:
上海阿拉丁生化科技股份有限公司
- CAS号:
20357-25-9
- 规格:
N138447-5g/N138447-25g/N138447-100g/N138447-500g/N138447-10g
| 规格: | N138447-5g | 产品价格: | ¥40.9 |
|---|---|---|---|
| 规格: | N138447-25g | 产品价格: | ¥194.9 |
| 规格: | N138447-100g | 产品价格: | ¥1329.9 |
| 规格: | N138447-500g | 产品价格: | ¥2689.9 |
| 规格: | N138447-10g | 产品价格: | ¥171.9 |
DMNB (4,5-dimethoxy-2-nitrobenzaldehyde) is a cell-permeable vanillin derivative and potent inhibitor of DNA-PK (IC50 = 15 μM). DMNB is shown in experiments to increase DR4/DR5 mRNA levels and their surface expression and decrease c-FLIP mRNA levels in K56. DMNB is also an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair.6-Nitroveratraldehyde has been used in the preparation of: · no-carrier-added 6-18F-fluoro-L-dopa, fundamental tracer for cerebral positron emission tomography studies of dopaminergic system in humans · o-nitroaryl-bis(5-methylfur-2-yl)methanes, versatile synthons for the synthesis of nitrogen-containing heterocycles
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