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文献和实验Clustering of Gene Expression Data Via Normal Mixture Models
of the tissues (gene profiles). The clusters of tissues so obtained in the first problem can play a useful role in the discovery and understanding of new subclasses of diseases. The clusters of genes obtained in the second problem can be used to search
Mutation and Polymorphism Detection: A Technical Overview
for mutation detection. Therefore, many different methods have been developed for detecting new mutations and screening populations for known mutations or polymorphisms. Traditional mutation detection systems, such as restriction fragment length polymorphism
RHD Genotyping from Maternal Plasma: Guidelines and Technical Challenges
reaction (PCR)-based tests were devised to characterize free fetal DNA in maternal plasma and serum, and RHD genotyping was a convenient assay to develop this exciting new technology, because the accuracy of tests could easily be confirmed after the simple
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