- ￥1080 - 22680
- Sino Biological
- 北京
- 10561-HNCH
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human GDNF Protein
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/10.00 µg/20.00 µg/100.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥22680.0 |
|---|---|---|---|
| 规格： | 10.00 µg | 产品价格： | ￥1080.0 |
| 规格： | 20.00 µg | 产品价格： | ￥1780.0 |
| 规格： | 100.00 µg | 产品价格： | ￥3480.0 |
GDNF重组蛋白|Recombinant Human GDNF Protein（产品说明）
蛋白名称：Human GDNF Protein
蛋白构建：A DNA sequence encoding the mature form of human GDNF (P39905-2) (Arg 83-Ile 185) was expressed and purified, with additional two aa (Gly& Pro) at the N-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 97 % as determined by SDS-PAGE
蛋白活性：1. Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is typically 0.3-3 ng/mL in the presence of Recombinant Human GFR alpha‑1/GDNF R alpha‑1 His Chimera. 2. Immobilized Recombinant Human GDNF Protein(Cat:10561-HNCH) at 2 μg/mL (100 μL/well) can bind Recombinant Human GFRA1 / GFRα1 / GDNFRA Protein (His Tag) (Cat:10330-H08H), the EC50 is 15-48 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gly
蛋白分子量：The recombinant human GDNF consists of 105 amino acids and predicts a molecular mass of 15.1 KDa. It migrates as approximately 18 KDa band in SDS-PAGE under reducing conditions.
蛋白NP号：P39905-2
蛋白氨基酸序列：Arg83-Ile185
蛋白名称：Human GDNF Protein
蛋白构建：A DNA sequence encoding the mature form of human GDNF (P39905-2) (Arg 83-Ile 185) was expressed and purified, with additional two aa (Gly& Pro) at the N-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 97 % as determined by SDS-PAGE
蛋白活性：1. Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is typically 0.3-3 ng/mL in the presence of Recombinant Human GFR alpha‑1/GDNF R alpha‑1 His Chimera. 2. Immobilized Recombinant Human GDNF Protein(Cat:10561-HNCH) at 2 μg/mL (100 μL/well) can bind Recombinant Human GFRA1 / GFRα1 / GDNFRA Protein (His Tag) (Cat:10330-H08H), the EC50 is 15-48 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gly
蛋白分子量：The recombinant human GDNF consists of 105 amino acids and predicts a molecular mass of 15.1 KDa. It migrates as approximately 18 KDa band in SDS-PAGE under reducing conditions.
蛋白NP号：P39905-2
蛋白氨基酸序列：Arg83-Ile185
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文献和实验该产品被引用文献
1, Cheng X, et al. Astrocytes modulate brain phosphate homeostasis via polarized distribution of phosphate uptake transporter PiT2 and exporter XPR1.Neuron, PubMed ID: 39019040
2, Fagiani F, et al. A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis.Cell reports. Medicine, PubMed ID: 39121861
2, Fagiani F, et al. A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis.Cell reports. Medicine, PubMed ID: 39121861
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GDNF重组蛋白|Recombinant Human GDNF Protein
￥1080 - 22680
