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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
"-20°C/-80°C"
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
- 英文名:
Customized Human ICOSLG Protein (in vitro E.coli)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20ug
Alternative Name(s)
ICOS ligand Alternative name(s): B7 homolog 2; B7-H2 B7-like protein Gl50 B7-related protein 1; B7RP-1 CD_antigen= CD275Editorial/Sponsord
EditorialUniprot ID
O75144Gene Names
ICOSLGOrganism
HumanAASequence
DTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVCRDRCLQHSYAGAWAVSPETELTGHVExpression Region
19-302aaSequence Info
Full lengthSource
in vitro E.coliSource Notice
Mammalian cell expression systems and other species are available. Please inquire.Tag Info
InquireMW
InquireList Price
1616Purity
Greater than 85% as determined by SDS-PAGE.Storage Buffer
Tris/PBS-based buffer, 6% TrehaloseStorage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.Endotoxin
Not Test. Endotoxin removal service is available for free upon you request.产品类型
Transmembrane-Protein备注
**产品信息可能有变动,请以官网信息为准
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文献和实验**产品信息可能有变动,请以官网信息为准
性体液免疫和细胞免疫。最近又发现,CD28-B7家族的新成员,包括:ICOS(inducible costimulator)及其配体B7RP-1以及PD-1(programmed death-1)及其配体PD-L1和PD-L2。CD28和ICOS可传递协同刺激(阳性)信号;而CTLA-4和PD-1则传递抑制性(阴性)信号。T细胞活化的阳性和阴性信号之间的平衡,对机体抵抗外来抗原的入侵,防止自身免疫反应的发生起着关键作用。PD-1—PD-L是最近在抑制性协同刺激通路方面的新进展。1 PD-1及其配体的结构和表达
Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) for Cellular Retinoid-Binding Proteins
primers. In addition, the regulation of expression of these genes may be studied by quantitative RT-PCR using primers optimized for specificity, as an alternative to conventional Northern blotting. This chapter is based on our experience in clonmg human
Characterization of Chemokine Receptors
a whole‐cell assay. The competition is homologous in that the radiolabeled and unlabeled ligand are both human TARC, which is species cross‐reactive such that it also binds to the murine CCR4 receptor. The IC50 value obtained in this experiment is 0.9 nM
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