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- 文献和实验
- 技术资料
- 保存条件：
常温
- 保质期：
一年
- 英文名：
GSK2983559 active metabolite
- 库存：
100
- 供应商：
科淼生物
- CAS号：
1423186-80-4
- 规格：
5mg
产品中文名称：GSK2983559 active metabolite
产品英文名称：GSK2983559 active metabolite
CAS号：1423186-80-4
纯度级别：≥98%
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文献和实验, we may find much more references regarding this issue. http://books.google.com/books?id=3mgPzNFjcWAC&pg=PA51&lpg=PA51&dq=gsk+tyrosine+phosphorylation+and+activity&source=bl&ots=x5ueTldpez&sig=CqRFJleXtEBn9OfelhODPAc28xs&hl=en&ei=KerNSu-XGcem8Abm-qmABA&sa=X&oi=book_result&ct
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
. 4.3 ). If all other regulationof GSK3 is constant (e.g. Tyr279/216 phosphorylation, Fig. 4.2a )then the threefold induction of Ser21/9 phosphorylation predictsan increase of stoichiometry at these sites from 0.1 to 0.3 mol/mol,since 67% of GSK3 remains active. Interestingly
-3b, sharing97% sequence similarity within their kinase catalytic domains(2) . In contrast to most kinases, GSK-3 is inactivated by phosphorylation(2) . GSK-3 is active in nonstimulated cells, whereasother kinases require cell stimulation for activation
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