- ￥1856 - 21236
- Arcegen
- 美国
- C230716
- 2026年04月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
负20度
- 保质期：
一年
- 英文名：
Recombinant Rhesus Macaque Fms-related Tyrosine Kinase 3 Ligand (Rhesus Macaque Flt-3 Ligand)
- 库存：
现货
- 供应商：
上海魔兜儿
- 规格：
10ug/100ug/500ug
| 规格： | 10ug | 产品价格： | ￥1856.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥10840.0 |
| 规格： | 500ug | 产品价格： | ￥21236.0 |
产品参数
|
别名（Synonyms） | Receptor-type tyrosine-protein kinase FLT3, FL cytokine receptor |
|
Accession | H9Z6V7 |
|
GeneID | 719239 |
|
表达系统（Source） | E.coli-derived Rhesus Macaque Fms-related Tyrosine Kinase 3 Ligand protein, Thr27-Pro185 |
|
分子量大小（Molecular Weight） | Approximately 18.0 kDa. |
|
氨基酸序列(AA Sequence) | TQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVPSNLQDEELCGALWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQHPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLP PPRSPGALEA TALTAPQRP |
|
标签（Tag） | None |
|
外观（Physical Appearance） | Sterile Filtered White lyophilized (freeze-dried) powder. |
|
纯度（Purity） | > 97 % by SDS-PAGE and HPLC analyses. |
|
生物活性（Biological Activity） | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human AML5 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg. |
|
内毒素（Endotoxin） | < 1.0 EU per 1μg of the protein by the LAL method. |
|
制剂（Formulation） | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4. |
|
复溶（Reconstitution） | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
储存条件
产品用冰袋装运，可在-20℃至-80℃下保存1年。
建议第一次使用时将蛋白质分成较小的量，并避免反复冻融循环。
注意事项
1.避免反复冻融循环。
2.为了您的安全和健康，请穿实验服，戴一次性手套进行操作。
3.仅供研究使用！
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文献和实验Immunohistochemical Determination of EGFR-Tyrosine Kinase Inhibition in Clinical Samples
, and an intracellular tyrosine-kinase (TK) domain (4 ). Binding of the ligands such as epidermal growth factor (EGF) and transforming growth factor α (TGFα) to the extracellular ligand-binding domain results in receptor dimerization, activation of its intrinsic TK
Tyrosine Kinase Inhibitors Against EGF Receptor-Positive Malignancies
epidermal growth factor receptor (EGFR) (1 –6 ), Janus kinases (JAKs) (7 –13 ), Bruton’s tyrosine kinase (BTK) (14 –16 ), platelet-derived growth factor (PDGF) (17 ), protein kinase C (PKC) (18 –24 ), Lck (25 , 26 ), Trk (27 –30
Analysis of Receptor Tyrosine Kinase Internalization Using Flow Cytometry
The internalization of activated receptor tyrosine kinases (RTKs) by endocytosis and their subsequent down regulation in lysosomes plays a critical role in regulating the duration and intensity of downstream signaling events. Uncoupling
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