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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
常温
- 保质期:
一年
- 英文名:
Ubiquitin Isopeptidase Inhibitor I, G5
- 库存:
100
- 供应商:
科淼生物
- CAS号:
108477-18-5
- 规格:
5mg
产品中文名称:Ubiquitin Isopeptidase Inhibitor I, G5
产品英文名称:Ubiquitin Isopeptidase Inhibitor I, G5
CAS号:108477-18-5
纯度级别:≥98%
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文献和实验Studies of the Ubiquitin Proteasome System
with Nonradioactive Tag (Biotin) Alternate Protocol 10: Generation of Tagged Ubiquitin Expression Plasmids Basic Protocol 18: Immunoblotting with Anti‐Ubiquitin Generation and Purification of Rabbit Anti‐Ubiquitin Antibodies Basic Protocol 19: Generation
A Method for Assaying Deubiquitinating Enzymes
form from 125 I-labeled Ub-PESTc. The purified enzyme was incubated with the radioiodinated substrate for various periods in the absence and presence of Ub-aldehyde, which is known as a specific inhibitor of DUBs (26 ). Table 1 shows that the acid
can be selectively inhibited by targeting the catalytic site with drug?like compounds. Notably, the mammalian 26S proteasome is associated with three major DUBs: RPN11, UCH37, and USP14. Because the ubiquitin ?chain?trimming? activity of USP14 can inhibit proteasome
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