Anti-Avelumab Polyclonal Antibody

Anti-Avelumab Polyclonal Antib

ody
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  • ¥2108
  • abinscience
  • France
  • AV974024
  • 2025年07月12日
  • Avelumab
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    • 详细信息
    • 技术资料
    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

    • 克隆性

      Polyclonal

    • 保质期

      1 year

    • 抗原来源

      Rabbit

    • 目录编号

      AV974024

    • 级别

      科研级别

    • 库存

      999

    • 供应商

      abinscience

    • 宿主

      Avelumab

    • 浓度

      1mg/ml

    • 抗体英文名

      Anti-Avelumab Polyclonal Antibody

    • 抗体名

      Anti-Avelumab Polyclonal Antibody

    • 规格

      50ug

    Anti-Avelumab Polyclonal Antib

    Product nameAnti-Avelumab Polyclonal Antibody
    Catalog No.AV974024
    Host speciesRabbit
    SpecificityThe product is specific for Avelumab. This antibody serves as an excellent positive control for Avelumab immunogenicity (ADA) assays.
    Conjugation\
    Species reactivity\
    ImmunogenAvelumab
    FormLiquid
    Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
    Purity\
    ClonalityPolyclonal
    IsotypeIgG
    ApplicationsELISA
    TargetRabbit polyclonal to Bavencio.
    PurificationPurified by antigen affinity column.
    AccessionCAS: 1537032-82-8
    Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
    BackgroundAvelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as
    Alternative Names\
    Clone ID\
    Species\
    NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.

    Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.

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