- ￥2588
- abinscience
- France
- HY257326
- 2026年03月03日
- Research Grade Biosimilar
- Human
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
0.01M PBS,pH7.4.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
1 year
- 抗原来源：
Human
- 目录编号：
HY257326
- 级别：
科研级别
- 库存：
999
- 供应商：
abinscience
- 宿主：
Human
- 应用范围：
Research Grade Biosimilar
- 浓度：
1 mg/ml
- 靶点：
B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20
- 抗体英文名：
Research Grade Anti-Human CD20/MS4A1 (GNR-006)
- 抗体名：
Research Grade Anti-Human CD20/MS4A1 (GNR-006)
- 规格：
100ug
| Product name | Research Grade Anti-Human CD20/MS4A1 (GNR-006) |
|---|---|
| Catalog No. | HY257326 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | P11836 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1030°C. |
| Alternative Names | GNR-006,GNR006,GNR006 |
| Species | \ |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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文献和实验因为抗体的结合而减少；在人体血清中无游离的CD20存在；最重要的是B淋巴细胞瘤上的CD20少有内吞和脱落的发生[ 2-5 ] 。1997年，以CD20为靶点的嵌合抗CD20单克隆抗体Rituxan已获准应用于B细胞淋巴瘤的治疗[ 6 ]。HI47（IgG3）是我所于1990年研制成功的国内第一个抗CD20鼠源性单克窿抗体，第四届国际人类白细胞分化抗原会议将HI47命名为CD20+X[ 7 ] 。我们利用噬菌体显示技术从HI47杂交瘤细胞中克隆到抗CD20抗体HI47可变区基因，将该基因构建成为嵌合的抗
；7：711[6] 杨希峰，沈德诚，金宇光等. HI47，一种人成熟B细胞单克隆抗体制备，鉴定及其生物特性研究。上海免疫学杂志，1990；10（2）：65-68[7] McLaughlin P，Grillo-Lopez AJ， Link BK，et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma：half of patient respond to a four-dose
Intracellular Cytokine Staining Protocol
anti-cytokine antibodies with excess amounts of unlabeled antibody. Alternatively, recombinant cytokines can be used for blocking.eBioscience antibodies are available as Functional Grade (FG) Purified (sterile, endotoxin-tested, no azide), Purified
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