Fmoc-Orn(ivDde)-OH

Solid-Phase Synthesis of Neuropeptides by Fmoc Strategies

an automated peptide synthesizer that performs solid-phase peptide synthesis using the Fmoc strategy (1 ). This is based on the sequential addition of amino acid residues to an insoluble polymeric support. The base-labile Fmoc group

Solid-Phase Guanidinylation of Peptidyl Amines Compatible with Standard Fmoc-Chemistry: Formation of Monosubstituted Guanidines

. Therefore, guanidinium functional group is considered as an important pharmacophoric element. Although a number of methods for solid-phase guanidinylation reactions exist, only a few are fully compatible with standard Fmoc solid-phase peptide

Synthesis of C-Terminal Peptide Thioesters Using Fmoc-Based Solid-Phase Peptide Chemistry

This chapter provides two protocols for the solid-phase synthesis of peptide thioesters using N α -Fmoc-protected amino acids. The first protocol is based on a so-called safety-catch linker, while the second relies on a backbone amide