- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- DMC100681P
- 2025年07月10日
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Rabbit/Human Fc chimeric IgG1
- 形态：
Liquid
- 保存条件：
Store at 2°C-8°C for 6 months
- 克隆性：
Monoclonal
- 标记物：
PE-conjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
仅用于科研
- 库存：
Under Development
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Rabbit
- 靶点：
CXCR2
- 抗体英文名：
PE-conjugated Anti-CXCR2 antibody(DMC681); IgG1 Chimeric mAb
- 抗体名：
PE-conjugated Anti-CXCR2 antibody(DMC681); IgG1 Chimeric mAb
- 规格：
100test
| SKU | DMC100681P |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 100 test ￥3880.00 |
| 背景 | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity; and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1:MGSA); a protein with melanoma growth stimulating activity; and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene; IL8RA; a gene encoding another high affinity IL8 receptor; as well as IL8RBP; a pseudogene of IL8RB; form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants; encoding the same protein; have been identified. [provided by RefSeq; Nov 2009] |
| Clone ID | DMC681 |
| 别名 | CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB |
| 应用 | Flow Cyt |
| 形态与组成成分 | Liquid，PBS with 0.05% Proclin300, 1% BSA |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | Flow Cyt 1:100 |
| 靶点 | CXCR2 |
| Uniprot ID | P25025; Q53PC4 |
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文献和实验Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
【翻译】Development trends for monoclonal antibody cancer therapeutics
antigens are targeted, the response should ultimately lead to destruction of the targeted cell. The mode of destruction can be direct (for example, via conjugated radioactive isotopes or toxins, or antibody triggered apoptosis) or indirect (for example
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