MUC16抗体/Anti-MUC16 antibody(3B11), IgG1 Chimeric mAb

MUC16抗体/Anti-MUC16 antibody(3B

11), IgG1 Chimeric mAb
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  • 询价
  • DIMA BIOTECH/缔码生物
  • 武汉
  • DMC101291
  • 2025年07月12日
  • Rabbit
  • Human
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    • 详细信息
    • 技术资料
    • 亚型

      Rabbit/Human Fc chimeric IgG1

    • 形态

      Powder

    • 保存条件

      Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human

    • 保质期

      12个月

    • 级别

      仅用于科研

    • 库存

      In Stock

    • 供应商

      缔码生物(武汉)科技有限公司

    • 宿主

      Rabbit

    • 靶点

      MUC16

    • 抗体英文名

      Anti-MUC16 antibody(3B11), IgG1 Chimeric mAb

    • 抗体名

      Anti-MUC16 antibody(3B11), IgG1 Chimeric mAb

    • 规格

      50μg

    SKU DMC101291
    产品分类 Monoclonal Antibodies
    规格 Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
    背景 This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. [provided by RefSeq, May 2017]
    Clone ID 3B11
    别名 CA125
    应用 Flow Cyt
    形态与组成成分 Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
    纯化方式 Purified from cell culture supernatant by affinity chromatography
    反应种属 Human
    推荐稀释比 Flow Cyt 1/100
    靶点 MUC16
    Uniprot ID Q8WXI7

    dmc101291-muc16-fc1.jpg

    Figure 1. Flow cytometry analysis with 1μg/mL Anti-MUC16 (3B11) mAb on Expi293 cells transfected with human MUC16 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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