- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- DMC100484
- 2025年07月06日
- Rabbit
- Human
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- 详细信息
- 技术资料
- 亚型：
Rabbit/Human Fc chimeric IgG1
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
仅用于科研
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Rabbit
- 靶点：
CDH1
- 抗体英文名：
Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb
- 抗体名：
Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb
- 规格：
50μg
| SKU | DMC100484 |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00 |
| 背景 | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric; breast; colorectal; thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation; invasion; and:or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq; Nov 2015] |
| Clone ID | DMC484 |
| 别名 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO |
| 应用 | Flow Cyt |
| 形态与组成成分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | Flow Cyt 1:100 |
| 靶点 | CDH1 |
| Uniprot ID | P12830 |
Figure 1. Flow cytometry analysis with Anti-CDH1 (DMC484) on Expi293 cells transfected with human CDH1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human CDH1 mAb( DMC100484). (A) DMC100484 does not bind to CHO-S cells that do not express CDH1. (B) A clear peak shift of DMC100484 was seen compared to the control when incubated with CDH1-expressing A431 cells, indicating strong binding of DMC100484 to CDH1. Antibodies were incubated at 5 μg/mL.
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CDH1抗体/Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb
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