EREG抗体/Anti-EREG antibody(DMC424); IgG1 Chimeric mAb

EREG抗体/Anti-EREG antibody(DMC4

24); IgG1 Chimeric mAb
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  • 询价
  • DIMA BIOTECH/缔码生物
  • 武汉
  • DMC100424
  • 2025年07月15日
  • Rabbit
  • Human
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    • 详细信息
    • 技术资料
    • 亚型

      Rabbit/Human Fc chimeric IgG1

    • 形态

      Powder

    • 保存条件

      Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human

    • 保质期

      12个月

    • 级别

      仅用于科研

    • 库存

      In Stock

    • 供应商

      缔码生物(武汉)科技有限公司

    • 宿主

      Rabbit

    • 靶点

      EREG

    • 抗体英文名

      Anti-EREG antibody(DMC424); IgG1 Chimeric mAb

    • 抗体名

      Anti-EREG antibody(DMC424); IgG1 Chimeric mAb

    • 规格

      50μg

    SKU DMC100424
    产品分类 Monoclonal Antibodies
    规格 Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
    背景 This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation; wound healing; oocyte maturation; and cell proliferation. Additionally; the encoded protein may promote the progression of cancers of various human tissues.
    Clone ID DMC424
    别名 Ep; EPR; ER
    应用 Flow Cyt
    形态与组成成分 Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
    纯化方式 Purified from cell culture supernatant by affinity chromatography
    反应种属 Human
    推荐稀释比 Flow Cyt 1:100
    靶点 EREG
    Uniprot ID O14944

    DMC100424-EREG-Flow-Fig1.jpg

    Figure 1. Flow cytometry analysis with Anti-EREG (DMC424) on Expi293 cells transfected with human EREG (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

    dmc100424-ereg-fc2.jpg

    Figure 2. Flow cytometry analysis of antigen binding of anti-human EREG mAb(DMC100424). (A) DMC100424 does not bind to Jurkat cells that do not express EREG. (B) A clear peak shift of DMC100424 was seen compared to the control when incubated with EREG-expressing SiHa cells, indicating strong binding of DMC100424 to EREG. Antibodies were incubated at 5 μg/mL.

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