- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- DME100193
- 2025年07月11日
- Rabbit
- Human
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- 详细信息
- 技术资料
- 亚型：
Rabbit IgG
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
仅用于科研
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Rabbit
- 靶点：
CD45
- 抗体英文名：
Anti-CD45 antibody(DM193); Rabbit mAb
- 抗体名：
Anti-CD45 antibody(DM193); Rabbit mAb
- 规格：
50μg
| SKU | DME100193 |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00 |
| 背景 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitosis; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported. |
| Clone ID | DM193 |
| 别名 | B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 |
| 应用 | ELISA; Flow Cyt |
| 形态与组成成分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | ELISA 1:5000-10000; Flow Cyt 1:100 |
| 靶点 | CD45 |
| Uniprot ID | P08575 |
Figure 1. Flow cytometry analysis with Anti-CD45 (DM193) on Expi293 cells transfected with human CD45 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of rabbit anti-human CD45 mAb(DME100193). (A) DME100193 does not bind to CHO-S cells that do not express CD45. (B) A clear peak shift of DME100193 was seen compared to the control when incubated with CD45-expressing Jurkat cells, indicating strong binding of DME100193 to CD45. Antibodies were incubated at 5 μg/mL.
Figure 3. Flow cytometry analysis of antigen binding of rabbit anti-human CD45 mAb(DME100193). (A) DME100193 does not bind to CHO-S cells that do not express CD45. (B) A clear peak shift of DME100193 was seen compared to the control when incubated with CD45-expressing THP-1 cells, indicating strong binding of DME100193 to CD45. Antibodies were incubated at 5 μg/mL.
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CD45抗体/Anti-CD45 antibody(DM193); Rabbit mAb
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