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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
Rabbit IgG
- 形态:
Powder
- 保存条件:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12个月
- 级别:
仅用于科研
- 库存:
In Stock
- 供应商:
缔码生物(武汉)科技有限公司
- 宿主:
Rabbit
- 靶点:
CLDN18.2
- 抗体英文名:
Anti-CLDN18.2 antibody(DM179); Rabbit mAb
- 抗体名:
Anti-CLDN18.2 antibody(DM179); Rabbit mAb
- 规格:
50μg
| SKU | DME100179 |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00 |
| 背景 | CLDN18 belongs to the large claudin family of proteins; which form tight junction strands in epithelial cells. |
| Clone ID | DM179 |
| 别名 | Claudin 18.2 |
| 应用 | ELISA; Flow Cyt |
| 形态与组成成分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | ELISA 1:5000-10000; Flow Cyt 1:100 |
| 靶点 | CLDN18.2 |
| Uniprot ID | P56856 |

Figure 1. Flow cytometry analysis with Anti-CLDN18.2 (DM179) on Expi293 cells transfected with human CLDN18.2 (Blue histogram)or Expi293 transfected with human CLDN18.1 (Green histogram)or Expi293 transfected with irrelevant protein (Red histogram).
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文献和实验[1] Xue W, Xu C, Zhang K, et al. Enhancing antitumor efficacy of CLDN18.2-directed antibody-drug conjugates through autophagy inhibition in gastric cancer. Cell Death Discov. 2024 Sep 3;10(1):393. doi: 10.1038/s41420-024-02167-0.
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