- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- DME100108
- 2025年07月12日
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Rabbit IgG
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
仅用于科研
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Rabbit
- 靶点：
CSF1R
- 抗体英文名：
Anti-CSF1R antibody(DM108); Rabbit mAb
- 抗体名：
Anti-CSF1R antibody(DM108); Rabbit mAb
- 规格：
50μg
| SKU | DME100108 |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00 |
| 背景 | The protein encoded by this gene is the receptor for colony stimulating factor 1; a cytokine which controls the production; differentiation; and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1:PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL); HL cell lines and anaplastic large cell lymphoma. |
| Clone ID | DM108 |
| 别名 | CSF1R;C-FMS;CD115;CSFR;FIM2;FMS;M-CSFR |
| 应用 | ELISA; Flow Cyt |
| 形态与组成成分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | ELISA 1:5000-10000; Flow Cyt 1:100 |
| 靶点 | CSF1R |
| Uniprot ID | P07333 |
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CSF1R protein,His tagged protein PME100067 can bind Rabbit anti- CSF1R monoclonal antibody (clone: DM108) in a linear range of 0.6-16 ng/ml.
Figure 2. Flow cytometry analysis with Anti-CSF1R (DM108) on Expi293 cells transfected with human CSF1R (Blue histogram)or Expi293 transfected with irrelevant protein (Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of rabbit anti-human CSF1R mAb(DME100108). (A) DME100108 does not bind to CHO-S cells that do not express CSF1R. (B) A clear peak shift of DME100108 was seen compared to the control when incubated with CSF1R-expressing THP-1 cells, indicating strong binding of DME100108 to CSF1R. Antibodies were incubated at 5 μg/mL.
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