- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- FLP120237
- 2025年09月28日
企业认证
相关产品推荐更多 >
SSTR2全长蛋白/Human SSTR2-Strep full length protein-synthetic nanodisc
询价
CLDN6全长蛋白/Human CLDN6-Strep full length protein-PeptiNanodisc
￥6300
CXCR4全长蛋白/Human CXCR4-Strep full length protein-synthetic nanodisc
￥5670
FXYD5全长膜蛋白/Human FXYD5-Strep full length protein-synthetic nanodisc
询价MC1R全长蛋白/Human MC1R-Strep full length protein-synthetic nanodisc
询价
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C to -80°C
- 保质期：
收货之日起12个月
- 英文名：
Human FFAR3-Strep full length protein-synthetic nanodisc
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10 μg///50 μg///100 μg
| 产品类别 | Full Length Transmembrane Proteins |
|---|---|
| 背景 | G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins. Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. |
| 货期 | In Stock |
| 描述 | Human FFAR3-Strep full length protein-synthetic nanodisc |
| 分子量 | The human full length FFAR3-Strep protein has a MW of 38.6 kDa |
| 蛋白家族 | Druggable Genome, GPCR, Transmembrane |
| 信号通路 | N/A |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 别名 | FFA3R; GPR41; GPR42 |
| 标签 | C-Flag&Strep Tag |
| 偶联情况 | Unconjugated |
| 表达宿主 | HEK293 |
| 组成成分 | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| 靶点 | FFAR3 |
| Uniprot ID | O14843 |
| 级别 | Research use only |
| 验证图 |  Figure 1. Elisa plates were pre-coated with C-Flag&Strep Tag FFAR3-Strep-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with FFAR3-Strep-nanodisc is 11.71ng/ml.  Figure 2. Human FFAR3-Strep-Nanodisc, C-Flag&Strep Tag on SDS-PAGE |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验三句话读懂一篇 CNS：晚睡晚起导致抑郁；吃药代替运动健身；高脂肪饮食引发结直肠癌...
结构 研究表明 LRRK2 蛋白酶突变是导致帕金森病的关键原因之一。 2021 年 6 月 8 日，圣裘德儿童研究医院孙吉教授团队在 Cell 上发表研究论文 Structural analysis of the full-length human LRRK2，该研究首次解析了人类 LRRK2 全长蛋白的高分辨率结构，为人类战胜帕金森病提供了理论参考。图 6：来源 Cell 7. Lacent: 父母学历越高，所生小孩死亡率越低 2021 年 6 月 10 日，挪威科技大学 Terje
receptor8. Mouse apoB is a large protein of 4,515 amino acids and is expressed predominantly in liver and jejunum. apoB mRNA is subject to post-transcriptional editing, and the unedited and edited transcripts encode the full-length protein apoB-100
位点，RNA聚合酶在此和DNA结合，并由此开始转录过程。 蛋白质（Protein）：一种由一条或者多条肽链构成的大分子。每条肽链上核苷酸的顺序是由基因外显子部分的碱基序列决定的。蛋白质是细胞、组织和器官的重要组成部分，每种蛋白质都具有特定的功能。酶、抗体和激素等都是蛋白质。 嘌呤（Purine）：一种含氮的单环结构物。是核苷酸的重要组成部分，有腺嘌呤A和鸟嘌呤G两种。 嘧啶（Pyrimidine）：一种含氮的双环结构，是核苷酸的重要组成部分。分为胞嘧啶C，胸腺嘧啶T和尿嘧啶U三种
技术资料暂无技术资料 索取技术资料
