- ¥5670.0¥3969限时7折！
- DIMA BIOTECH/缔码生物
- 武汉
- FLP120008
- 2025年09月28日
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- 详细信息
- 技术资料
- 保存条件：
-20°C to -80°C
- 保质期：
12个月
- 英文名：
Human CLDN6-Strep full length protein-synthetic nanodisc
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10μg
| 货号 | FLP120008 |
|---|---|
| 产品分类 | Full Length Transmembrane Proteins |
| 价格&规格 | Price: 10 μg ￥5670.00 ; 50 μg ￥27000.00 ; 100 μg ￥49500.00 |
| 背景 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
| 描述 | Human CLDN6-Strep full length protein-synthetic nanodisc |
| 分子量 | The human full length CLDN6-Strep Protein has a MW of 23.3 kDa |
| 蛋白家族 | Transmembrane |
| 信号通路 | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| 别名 | Claudin 6, Claudin-6, Skullin,Claudin6 |
| 标签 | C-Flag&Strep Tag |
| 是否偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 形式 | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| 靶点 | CLDN6 |
| Uniprot ID | P56747 |
| 用途 | Research use only |
验证图
Figure 1. Elisa plates were pre-coated with C-Flag&Strep Tag CLDN6-Strep-Nanodisc (0.2μg/per well). Serial diluted anti-CLDN6 monoclonal antibody (BME100082) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CLDN6 monoclonal antibody binding with CLDN6-Strep-Nanodisc is 334.6ng/ml. 
Figure 2. Human CLDN6-Strep-Nanodisc, C-Flag&Strep Tag on SDS-PAGE
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CLDN6全长蛋白/Human CLDN6-Strep full length protein-synthetic nanodisc
¥5670.0¥3969限时7折！
