TLR5全长蛋白/Human TLR5 full lengt

货号	FLP200143
产品分类	Full Length Transmembrane Proteins
价格&规格	Price: 50 μg ￥8000.00 ; 100 μg ￥10800.00
背景	Toll-like receptor (TLR) family plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
描述	Human TLR5 full length protein-MNP
分子量	The human full length TLR5 protein has a MW of 97.8 kDa
蛋白家族	Druggable Genome, Transmembrane
信号通路	Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway
别名	MELIOS; SLE1; SLEB1; TIL3
标签	N/A
是否偶联	Unconjugated
表达宿主	HEK293
形式	Lyophilized from PBS. Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
靶点	TLR5
Uniprot ID	O60602
用途	Research use only

验证图

Figure 1. Elisa plates were pre-coated with 0.5μg/per well purified human TLR5 full length membrane nanoparticles. Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TLR5 full length membrane nanoparticles is 12.46ng/ml.