CCR7全长蛋白/Human CCR7 full lengt

货号	FLP200060
产品分类	Full Length Transmembrane Proteins
价格&规格	Price: 50 μg ￥8000.00 ; 100 μg ￥10800.00
背景	The protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis.
描述	Human CCR7 full length protein-MNP
分子量	The human full length CCR7 protein has a MW of 42.9 kDa
蛋白家族	Druggable Genome, GPCR, Transmembrane
信号通路	Chemokine signaling pathway, Cytokine-cytokine receptor interaction
别名	BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1
标签	N/A
是否偶联	Unconjugated
表达宿主	HEK293
形式	Lyophilized from PBS. Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
靶点	CCR7
Uniprot ID	P32248
用途	Research use only

验证图

Figure 1. Elisa plates were pre-coated with 0.5μg/per well purified human CCR7 full length membrane nanoparticles. Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CCR7 full length membrane nanoparticles is 5.185ng/ml.