- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- FLP200139
- 2025年07月12日
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- 文献和实验
- 技术资料
- 保存条件：
-20°C to -80°C
- 保质期：
12个月
- 英文名：
Human FZD4 full length protein-MNP
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
50μg
| 货号 | FLP200139 |
|---|---|
| 产品分类 | Full Length Transmembrane Proteins |
| 价格&规格 | Price: 50 μg ￥8000.00 ; 100 μg ￥10800.00 |
| 背景 | A member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. |
| 描述 | Human FZD4 full length protein-MNP |
| 分子量 | The human full length FZD4 protein has a MW of 60.3 kDa |
| 蛋白家族 | Druggable Genome, GPCR, Transmembrane |
| 信号通路 | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| 别名 | CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4 |
| 标签 | N/A |
| 是否偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 形式 | Lyophilized from PBS. Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| 靶点 | FZD4 |
| Uniprot ID | Q9ULV1 |
| 用途 | Research use only |
验证图
Figure1. Elisa plates were pre-coated with 0.5μg/per well purified human FZD4 full length membrane nanoparticles. Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with FZD4 full length membrane nanoparticles is 13.75ng/ml.
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