ADGRE5全长蛋白/Human ADGRE5 full l

货号	FLP100117
产品分类	Full Length Transmembrane Proteins
价格&规格	Price: 10 μg ￥6300.00 ;50 μg ￥30000.00 ; 100 μg ￥55000.00
背景	A member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
描述	Human ADGRE5 full length protein-synthetic nanodisc
分子量	The human full length ADGRE5 protein has a MW of 90.5 kDa
蛋白家族	Druggable Genome, GPCR, Transmembrane
信号通路	N/A
别名	CD97; TM7LN1
标签	C-Flag Tag
是否偶联	Unconjugated
表达宿主	HEK293
形式	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
靶点	ADGRE5
Uniprot ID	P48960
用途	Research use only

验证图

Figure1. Elisa plates were pre-coated with Flag Tag ADGRE5-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with ADGRE5-Nanodisc is 7.327ng/ml.



Figure2. Human ADGRE5-Nanodisc, Flag Tag on SDS-PAGE